Reporter brief
Diet quality associated with lower CVD incidence and mortality, partially mediated by slower aging in UK cohort study
What happened
This prospective cohort study of 52,718 UK Biobank participants followed for a mean of 12 years examined whether accelerated biological aging mediated the association between diet quality (measured by four indices including Mediterranean Diet Score) and cardiovascular disease outcomes. Higher diet quality was associated with lower CVD incidence and mortality, with accelerated aging mediating 21.81–40.84% of the association with incident CVD and 16.67–35.87% of the association with CVD mortality.
Why it matters
Assessment pending; this report does not establish a change in evidence.
What it does NOT prove
- Limitations have not been recorded; consult the primary source.
Study design and sample
Cohort; Human.
UK Biobank cohort participants
- Design
- Cohort
- Sample
- 52,718
- Journal
- GeroScience
- Published
- Sep 20, 2026
Effect size
Proportion mediated ranged from 21.81 to 40.84% for incident CVD and from 16.67 to 35.87% for CVD mortality
Caveats
- Assessment: Superseded.
- Only the source material recorded on this evidence page was assessed.
Conflicts and funding
Not recorded.
Previous evidence
See the Mediterranean diet timeline and recorded assessment for prior evidence.
Primary source
Cancel Death charts and briefs may be reproduced editorially with attribution to CancelDeath.com. This brief is generated from the primary recorded source facts and assessment. Its review status is shown below; verify quotations against the paper before publication.