Reporter brief
Evidence-Based Longevity Interventions and Targeted Engagement (E.L.I.T.E.)
What happened
Trial registry update: COMPLETED. No results reported in the supplied registry record.
Why it matters
Assessment pending; this report does not establish a change in evidence.
What it does NOT prove
- The abstract does not report whether either intervention improved the primary outcome (MIC-C change) or how the two arms compared to each other.
- The study was not blinded and had no control arm, so any observed changes cannot be distinguished from placebo or natural variation.
- With 31 participants across two active arms, the study was underpowered to detect clinically meaningful differences; this was explicitly a pilot feasibility study.
Study design and sample
Rct; Human.
Community-dwelling adults aged 50 to 80 years without diabetes and with a body-mass index of at least 25 kg/m2
- Design
- Rct
- Sample
- 31
- Journal
- Sheba Medical Center
- Published
- Oct 13, 2026
Effect size
Not recorded.
Caveats
- Assessment: Unassessed.
- Only the source material recorded on this evidence page was assessed.
Conflicts and funding
Not recorded.
Previous evidence
See the Metformin timeline and recorded assessment for prior evidence.
Primary source
Cancel Death charts and briefs may be reproduced editorially with attribution to CancelDeath.com. This brief is generated from the primary recorded source facts and assessment. Its review status is shown below; verify quotations against the paper before publication.