Reporter brief
Exercise combined with spermidine and rapamycin or lamivudine was feasible in Phase 1b trial
What happened
This Phase 1b RCT assessed the safety and feasibility of combining exercise, spermidine supplementation, and either rapamycin or lamivudine in participants. The study evaluated whether this multi-component intervention could be delivered as designed and was tolerated, as a precursor to testing effects on inflammation and aging markers.
Why it matters
Assessment pending; this report does not establish a change in evidence.
What it does NOT prove
- Limitations have not been recorded; consult the primary source.
Study design and sample
Rct; Human.
Not recorded.
- Design
- Rct
- Sample
- —
- Journal
- Icahn School of Medicine at Mount Sinai
- Published
- Aug 27, 2026
Effect size
Not recorded.
Caveats
- Assessment: Superseded.
- Only the source material recorded on this evidence page was assessed.
Conflicts and funding
Not recorded.
Previous evidence
See the Exercise timeline and recorded assessment for prior evidence.
Primary source
Cancel Death charts and briefs may be reproduced editorially with attribution to CancelDeath.com. This brief is generated from the primary recorded source facts and assessment. Its review status is shown below; verify quotations against the paper before publication.