Reporter brief
FEAST and HOPE: Redox PSC Pilot Study in PSC
What happened
Trial registry update: NOT_YET_RECRUITING. No results reported in the supplied registry record.
Why it matters
Assessment pending; this report does not establish a change in evidence.
What it does NOT prove
- No control or comparison group means any changes in liver tests cannot be distinguished from natural disease fluctuation or placebo response. The intervention combines four agents plus dietary modification, so individual contributions cannot be isolated. The study was explicitly not designed to show that the combination treats PSC, and effect sizes were not reported.
Study design and sample
Other; Human.
Adults aged 18 to 70 with primary sclerosing cholangitis (PSC)
- Design
- Other
- Sample
- 15
- Journal
- Brigham and Women's Hospital
- Published
- Oct 27, 2026
Effect size
Not recorded.
Caveats
- Assessment: Unassessed.
- Only the source material recorded on this evidence page was assessed.
Conflicts and funding
Not recorded.
Previous evidence
See the Nicotinamide riboside timeline and recorded assessment for prior evidence.
Primary source
Cancel Death charts and briefs may be reproduced editorially with attribution to CancelDeath.com. This brief is generated from the primary recorded source facts and assessment. Its review status is shown below; verify quotations against the paper before publication.