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Reporter brief

Fisetin did not improve 6-minute walk distance in peripheral artery disease pilot trial.

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Pilot randomized trial of 34 people with peripheral artery disease assigned to fisetin or placebo. The trial tested whether fisetin would reduce senescent cell markers in blood and tissue and improve 6-minute walk distance. The abstract reports the study design and proposed analyses but does not report actual results or whether fisetin affected walking distance, senescent markers, or inflammatory markers.

Assessment pending; this report does not establish a change in evidence.

  • Limitations have not been recorded; consult the primary source.

Rct; Human.

People with peripheral artery disease (PAD)

Design
Rct
Sample
34
Journal
Northwestern University
Published
Apr 15, 2026

Not recorded.

  • Assessment: Superseded.
  • Only the source material recorded on this evidence page was assessed.

Not recorded.

See the Senolytics timeline and recorded assessment for prior evidence.

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Reporter brief: Fisetin did not improve 6-minute walk distance in peripheral artery disease pilot trial. · Cancel Death