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Reporter brief

Fisetin plus exercise versus placebo in breast cancer survivors for frailty prevention: phase II RCT

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This phase II randomized controlled trial tested fisetin (a dietary compound found in strawberries) combined with exercise against placebo for preventing frailty in breast cancer survivors. The trial was designed to evaluate whether fisetin could eliminate senescent cells—aged cells that stop dividing but persist in tissues—which are hypothesized to contribute to frailty through inflammatory pathways.

Assessment pending; this report does not establish a change in evidence.

  • Limitations have not been recorded; consult the primary source.

Rct; Human.

Breast cancer survivors

Design
Rct
Sample
—
Journal
Jonsson Comprehensive Cancer Center
Published
Jul 30, 2026

Not recorded.

  • Assessment: Superseded.
  • Only the source material recorded on this evidence page was assessed.

Not recorded.

See the Senolytics timeline and recorded assessment for prior evidence.

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