Reporter brief
Home-based prehabilitation improved 6-minute walk distance before surgery in prefrail/frail men: RCT.
What happened
A randomized controlled trial of 80 prefrail and frail men aged ≥60 undergoing radical prostatectomy compared short-term home-based multimodal prehabilitation (exercise, nutrition, psychology, pelvic floor training, breathing, health guidance) to usual care alone over a median 12-day preoperative period. The prehabilitation group improved 6-minute walk distance by 27.70 m from baseline to preoperatively, while usual care declined by 3.12 m, yielding a 30.82 m between-group difference (P < 0.001). Exploratory findings suggested faster early ambulation, gastrointestinal recovery, and shorter hospital stay.
Why it matters
Assessment pending; this report does not establish a change in evidence.
What it does NOT prove
- Limitations have not been recorded; consult the primary source.
Study design and sample
Rct; Human.
Men aged 60 or older with prostate cancer classified as prefrail or frail, scheduled for elective radical prostatectomy
- Design
- Rct
- Sample
- 80
- Journal
- BMC Geriatrics
- Published
- Jul 24, 2026
Effect size
Between-group difference in 6MWT change: 30.82 m (95% CI, 25.32 to 36.33; P < 0.001). Prehabilitation group: 27.70 ± 16.86 m improvement; usual care group: -3.12 ± 3.62 m change
Caveats
- Assessment: Superseded.
- Only the source material recorded on this evidence page was assessed.
Conflicts and funding
Not recorded.
Previous evidence
See the Exercise timeline and recorded assessment for prior evidence.
Primary source
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