Reporter brief
Klotho levels associated with bone density in women with systemic sclerosis: observational cross-sectional study
What happened
This observational cross-sectional study examined whether klotho and related cytokines are associated with bone mineral density and osteoimmunological markers in female patients aged 45-65 with systemic sclerosis, compared to age and gender-matched healthy controls. The study investigates whether these factors relate to the microvascular damage and fibrosis characteristic of systemic sclerosis. No effect sizes, sample sizes, or specific findings are reported in the abstract.
Why it matters
Assessment pending; this report does not establish a change in evidence.
What it does NOT prove
- Limitations have not been recorded; consult the primary source.
Study design and sample
Observational; Human.
Female patients aged 45-65 years with systemic sclerosis (SSc) diagnosed according to EULAR/ACR 2013 criteria and age and gender-matched healthy control subjects
- Design
- Observational
- Sample
- —
- Journal
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
- Published
- Mar 12, 2025
Effect size
Not recorded.
Caveats
- Assessment: Pending.
- Only the source material recorded on this evidence page was assessed.
Conflicts and funding
Not recorded.
Previous evidence
See the Klotho timeline and recorded assessment for prior evidence.
Primary source
Cancel Death charts and briefs may be reproduced editorially with attribution to CancelDeath.com. This brief is generated from the primary recorded source facts and assessment. Its review status is shown below; verify quotations against the paper before publication.