Linum strictum seed oil showed α-amylase inhibition comparable to acarbose in in vitro testing.
This in vitro study characterized the fatty acid composition of Linum strictum seed oil and tested its biological activities. The oil's α-amylase inhibition reached 85.98% with an IC50 of 0.0134 mg/mL, which the authors report as comparable to acarbose. The study also found antibacterial activity against several strains, >70% biofilm inhibition against A. baumannii, and anticoagulant effects.
What this changes
The finding has not established an approved change to our evidence assessment.
Source date: Sep 1, 2026 · Discovered: Sep 21, 2026 · Assessed: — · Research update
What it does not prove
- Limitations have not yet been verified. Read the primary source.
Extracted from supplied source material; model confidence is not a measured probability of correctness.
Study details
- Design
- In vitro
- Sample size
- —
- Duration
- —
- Population
- Linum strictum seed oil extracted from commercially obtained seeds; tested against bacterial strains including Pseudomonas aeruginosa, methicillin-resistant Staphylococcus aureus (MRSA), Acinetobacter baumannii, and Enterococcus faecalis ATCC 29212
- Primary outcome
- Antibacterial activity, antibiofilm activity, anticoagulant activity, and α-amylase inhibitory effects
- Effect size
- Antibacterial: MIC = 1.25 mg/mL (against E. faecalis ATCC 29212 and A. baumannii strains A2553 and A722); MIC = 5 mg/mL (S. aureus strains). Biofilm inhibition: >70% against A. baumannii at 2×MIC. Anticoagulant: PT = 16.4 s; aPTT = 81.6 s. α-Amylase inhibition: 85.98% (IC50 = 0.0134 mg/mL)
- Significance
- Not reported
- Journal
- Chemistry & Biodiversity
- Published
- Sep 1, 2026
Sources
Primary source
- Chemistry & biodiversity ↗Peer reviewed
Assessment history
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