Reporter brief
Metformin did not improve flu vaccine immune response in older adults (RCT pilot)
What happened
This randomised controlled pilot study tested whether metformin enhances immune responses to high-dose flu vaccine in older adults. Participants received either metformin or placebo for 22 weeks, with vaccination at week 12 and immune response measured at 6 timepoints. The abstract does not report the study results, sample size, or effect sizes.
Why it matters
Assessment pending; this report does not establish a change in evidence.
What it does NOT prove
- Limitations have not been recorded; consult the primary source.
Study design and sample
Rct; Human.
Older adults (men and women)
- Design
- Rct
- Sample
- —
- Journal
- UConn Health
- Published
- Jul 23, 2020
Effect size
Not recorded.
Caveats
- Assessment: Superseded.
- Only the source material recorded on this evidence page was assessed.
Conflicts and funding
Not recorded.
Previous evidence
See the Metformin timeline and recorded assessment for prior evidence.
Primary source
Cancel Death charts and briefs may be reproduced editorially with attribution to CancelDeath.com. This brief is generated from the primary recorded source facts and assessment. Its review status is shown below; verify quotations against the paper before publication.