Reporter brief
MOTIVATE study protocol: RCT of exercise and semaglutide on cognition in older adults with type 2 diabetes.
What happened
The MOTIVATE study is a randomized trial protocol examining supervised exercise (3 times weekly for 32 weeks) and semaglutide treatment (weekly injections for 16 weeks), alone or combined, versus control in older adults with type 2 diabetes. The study will measure cognitive function via testing, physical outcomes, metabolic markers, and brain imaging to evaluate whether these interventions support cognitive health and physical function in this population.
Why it matters
Assessment pending; this report does not establish a change in evidence.
What it does NOT prove
- Limitations have not been recorded; consult the primary source.
Study design and sample
Rct; Human.
Older adults with Type 2 diabetes
- Design
- Rct
- Sample
- —
- Journal
- Western University, Canada
- Published
- Aug 20, 2026
Effect size
Not recorded.
Caveats
- Assessment: Superseded.
- Only the source material recorded on this evidence page was assessed.
Conflicts and funding
Not recorded.
Previous evidence
See the Exercise timeline and recorded assessment for prior evidence.
Primary source
Cancel Death charts and briefs may be reproduced editorially with attribution to CancelDeath.com. This brief is generated from the primary recorded source facts and assessment. Its review status is shown below; verify quotations against the paper before publication.