Reporter brief
Nicotinamide Riboside Supplementation for Treating Elevated Systolic Blood Pressure and Arterial Stiffness in Middle-aged and Older Adults
What happened
Trial registry update: ACTIVE_NOT_RECRUITING. No results reported in the supplied registry record.
Why it matters
Assessment pending; this report does not establish a change in evidence.
What it does NOT prove
- The abstract does not specify the magnitude of the blood pressure or arterial stiffness changes in the main trial, making it unclear whether effects are clinically meaningful. The study enrolled only adults with mildly elevated blood pressure, so findings may not generalize to those with higher baseline pressure. Long-term effects beyond 3 months are unknown.
Study design and sample
Rct; Human.
Middle-aged and older men and women with systolic blood pressure between 120 and 139 mmHg at baseline
- Design
- Rct
- Sample
- —
- Journal
- Douglas Seals
- Published
- Oct 2, 2026
Effect size
Not recorded.
Caveats
- Assessment: Unassessed.
- Only the source material recorded on this evidence page was assessed.
Conflicts and funding
Not recorded.
Previous evidence
See the Nicotinamide riboside timeline and recorded assessment for prior evidence.
Primary source
Cancel Death charts and briefs may be reproduced editorially with attribution to CancelDeath.com. This brief is generated from the primary recorded source facts and assessment. Its review status is shown below; verify quotations against the paper before publication.