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Reporter brief

Phase II RCT of senolytics showed safety and feasibility in older adults with mild cognitive impairment or early Alzheimer's disease

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A Phase II randomized controlled trial evaluated senolytics in older adults with amnestic mild cognitive impairment or early-stage Alzheimer's disease who were tau PET positive. The study assessed safety, feasibility, and efficacy of the intervention. Specific efficacy results, sample size, and effect sizes were not reported in the available material.

Assessment pending; this report does not establish a change in evidence.

  • Limitations have not been recorded; consult the primary source.

Rct; Human.

Not recorded.

Design
Rct
Sample
—
Journal
Washington University School of Medicine
Published
Apr 1, 2026

Not recorded.

  • Assessment: Superseded.
  • Only the source material recorded on this evidence page was assessed.

Not recorded.

See the Senolytics timeline and recorded assessment for prior evidence.

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Reporter brief: Phase II RCT of senolytics showed safety and feasibility in older adults with mild cognitive impairment or early Alzheimer's disease · Cancel Death