Reporter brief
Pilot RCT of fisetin for vascular function in older adults reports no results.
What happened
This is a pilot randomised controlled trial designed to test whether intermittent fisetin treatment improves vascular endothelial function and reduces aortic stiffness in older adults. The trial aimed to explore potential mechanisms including mitochondrial oxidative stress, cellular senescence, and SASP factors. No results or findings are reported.
Why it matters
Assessment pending; this report does not establish a change in evidence.
What it does NOT prove
- Limitations have not been recorded; consult the primary source.
Study design and sample
Rct; Human.
Older adults
- Design
- Rct
- Sample
- —
- Journal
- University of Colorado, Boulder
- Published
- Sep 25, 2026
Effect size
Not recorded.
Caveats
- Assessment: Superseded.
- Only the source material recorded on this evidence page was assessed.
Conflicts and funding
Not recorded.
Previous evidence
See the Senolytics timeline and recorded assessment for prior evidence.
Primary source
Cancel Death charts and briefs may be reproduced editorially with attribution to CancelDeath.com. This brief is generated from the primary recorded source facts and assessment. Its review status is shown below; verify quotations against the paper before publication.