Reporter brief
RCT of everolimus (rapamycin analog) with or without resistance training on bone formation in postmenopausal women
What happened
This randomized controlled trial enrolled postmenopausal women aged 60-75 years in a 1:1:1:1 design comparing oral everolimus 5 mg weekly, placebo weekly, everolimus plus resistance training (3 hours weekly), or placebo plus resistance training. The study measured bone formation, muscle function, bone and muscle protein turnover, and quality of life through imaging, biopsies, blood samples, and functional testing across 5-7 visits. No results are reported in the material provided.
Why it matters
Assessment pending; this report does not establish a change in evidence.
What it does NOT prove
- Limitations have not been recorded; consult the primary source.
Study design and sample
Rct; Human.
Postmenopausal women aged 60-75 years
- Design
- Rct
- Sample
- —
- Journal
- Odense University Hospital
- Published
- Apr 6, 2026
Effect size
Not recorded.
Caveats
- Assessment: Superseded.
- Only the source material recorded on this evidence page was assessed.
Conflicts and funding
Not recorded.
Previous evidence
See the Rapamycin timeline and recorded assessment for prior evidence.
Primary source
Cancel Death charts and briefs may be reproduced editorially with attribution to CancelDeath.com. This brief is generated from the primary recorded source facts and assessment. Its review status is shown below; verify quotations against the paper before publication.