Reporter brief
RCT of metformin and lifestyle intervention in metabolic syndrome, results not reported
What happened
This was a Phase III randomized controlled trial in people with metabolic syndrome designed to test whether metformin and comprehensive lifestyle changes (moderate physical activity, Mediterranean/macrobiotic diet with calorie and protein restriction) prevent age-related chronic diseases. The abstract describes only the study design and aims; no results or outcomes are reported.
Why it matters
Assessment pending; this report does not establish a change in evidence.
What it does NOT prove
- Limitations have not been recorded; consult the primary source.
Study design and sample
Rct; Human.
Men and women with Metabolic syndrome (MetS)
- Design
- Rct
- Sample
- —
- Journal
- Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
- Published
- Sep 28, 2021
Effect size
Not recorded.
Caveats
- Assessment: Superseded.
- Only the source material recorded on this evidence page was assessed.
Conflicts and funding
Not recorded.
Previous evidence
See the Metformin timeline and recorded assessment for prior evidence.
Primary source
Cancel Death charts and briefs may be reproduced editorially with attribution to CancelDeath.com. This brief is generated from the primary recorded source facts and assessment. Its review status is shown below; verify quotations against the paper before publication.