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Reporter brief

RCT protocol for weekly rapamycin derivatives in older adults; results not yet reported

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RAP PAC is a randomised trial designed to identify safe weekly doses of sirolimus or everolimus in adults aged 55-89 without overt chronic disease. Participants receive 6 weeks of treatment at 5, 10, or 15 mg once weekly. This is a protocol description; no efficacy or safety outcomes have been reported.

Assessment pending; this report does not establish a change in evidence.

  • Limitations have not been recorded; consult the primary source.

Rct; Human.

Participants aged 55-89 years old that are free of overt chronic diseases

Design
Rct
Sample
—
Journal
University of Wisconsin, Madison
Published
May 28, 2026

Not recorded.

  • Assessment: Superseded.
  • Only the source material recorded on this evidence page was assessed.

Not recorded.

See the Rapamycin timeline and recorded assessment for prior evidence.

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