Reporter brief
RCT testing metformin effect on surgical outcomes in nondiabetic older adults, first adaptive platform trial study
What happened
A randomized controlled trial (SPRY study) embedded within an adaptive platform testing multiple interventions for elective surgery patients. The study aims to determine whether metformin improves surgical outcomes, specifically hospital-free days at day 90, in nondiabetic older adults undergoing elective surgery. No results are reported.
Why it matters
Assessment pending; this report does not establish a change in evidence.
What it does NOT prove
- Limitations have not been recorded; consult the primary source.
Study design and sample
Rct; Human.
Nondiabetic older adults scheduled for elective surgery
- Design
- Rct
- Sample
- —
- Journal
- Not peer-reviewed; author listed as Matthew Neal MD
- Published
- Jun 18, 2024
Effect size
Not recorded.
Caveats
- Assessment: Superseded.
- Only the source material recorded on this evidence page was assessed.
Conflicts and funding
Not recorded.
Previous evidence
See the Metformin timeline and recorded assessment for prior evidence.
Primary source
Cancel Death charts and briefs may be reproduced editorially with attribution to CancelDeath.com. This brief is generated from the primary recorded source facts and assessment. Its review status is shown below; verify quotations against the paper before publication.