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Registry update — unassessed

Semaglutide Given Before and After Conversion of Sleeve Gastrectomy to Roux-en-Y Gastric Bypass for Recurrent Weight Gain: a Randomized, Double-blind, Placebo-controlled Trial

Trial registry update: NOT_YET_RECRUITING. No results reported in the supplied registry record.

RCTMinor significance
Reporter brief

What this changes

The finding has not established an approved change to our evidence assessment.

Source date: Oct 5, 2026 · Discovered: Oct 5, 2026 · Assessed: — · Research update

What it does not prove

  • This is a protocol or background document, not a results report—no outcome data are presented.
  • The efficacy or safety of semaglutide in this specific population and timing cannot be assessed from this abstract.
  • Whether combining semaglutide with conversion surgery outperforms either intervention alone is not addressed in the material provided.

Extracted from supplied source material; model confidence is not a measured probability of correctness.

Design
Rct
Sample size
—
Duration
—
Population
Patients with recurrent weight gain after sleeve gastrectomy (SG)
Primary outcome
Weight loss comparison between semaglutide and conversion of sleeve gastrectomy to Roux-en-Y gastric bypass
Effect size
—
Significance
Not reported
Journal
General Committee of Teaching Hospitals and Institutes, Egypt
Published
Oct 5, 2026

Recorded source passages

Abstract or registry material supplied for assessment; source version 1. This is not a claim of full-text review.

Recurrent weight gain affects 15% to 40% of patients after metabolic and bariatric surgery (MBS). SG is the most performed operation worldwide, and long-term regain after SG is well documented.
Conversion of SG to RYGB gives around 20% additional total weight loss at 12 months across all indications
Semaglutide gives around 11% total weight loss
This protocol is that trial.

Assessment history

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