Reporter brief
SEN-SURVIVORS: An Open-Label Intervention Trial to Reduce Senescence and Improve Frailty in Adult Survivors of Childhood Cancer
What happened
Trial registry update: ACTIVE_NOT_RECRUITING. No results reported in the supplied registry record.
Why it matters
Assessment pending; this report does not establish a change in evidence.
What it does NOT prove
- No efficacy data are presented—this is a protocol or interim report, not a results paper. Open-label design without placebo control means results would be vulnerable to bias and placebo effects. The study is explicitly a pilot generating preliminary evidence; it cannot establish efficacy for the senolytic interventions or that they improve frailty in this population.
Study design and sample
Rct; Human.
Adult survivors of childhood cancer
- Design
- Rct
- Sample
- —
- Journal
- St. Jude Children's Research Hospital
- Published
- Sep 30, 2026
Effect size
Not recorded.
Caveats
- Assessment: Superseded.
- Only the source material recorded on this evidence page was assessed.
Conflicts and funding
Not recorded.
Previous evidence
See the Senolytics timeline and recorded assessment for prior evidence.
Primary source
Cancel Death charts and briefs may be reproduced editorially with attribution to CancelDeath.com. This brief is generated from the primary recorded source facts and assessment. Its review status is shown below; verify quotations against the paper before publication.