Reporter brief
Systematic review examines molecular mechanisms of skin aging and therapeutic approaches including stem cell therapy.
What happened
This is a narrative review that describes the phenotypes and mechanisms of skin aging, including reduced regenerative capacity, chronic inflammation, impaired barrier function, oxidative stress, DNA damage, and epigenetic alterations. The authors evaluate recent research on pharmacological interventions and stem cell therapy for mitigating skin aging, along with delivery systems for natural compounds and the potential of AI in drug discovery. No specific efficacy data or effect sizes for stem cell therapy are reported.
Why it matters
Assessment pending; this report does not establish a change in evidence.
What it does NOT prove
- Limitations have not been recorded; consult the primary source.
Study design and sample
Systematic review; Human.
Skin, the body's largest organ
- Design
- Systematic review
- Sample
- —
- Journal
- Journal of cellular and molecular medicine
- Published
- Sep 1, 2026
Effect size
Not recorded.
Caveats
- Assessment: Pending.
- Only the source material recorded on this evidence page was assessed.
Conflicts and funding
Not recorded.
Previous evidence
See the Stem cell therapy timeline and recorded assessment for prior evidence.
Primary source
Cancel Death charts and briefs may be reproduced editorially with attribution to CancelDeath.com. This brief is generated from the primary recorded source facts and assessment. Its review status is shown below; verify quotations against the paper before publication.