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Registry update — unassessed

Targeting Cellular Senescence With Fisetin for Improving Vascular Endothelial Function in Older Adults

Trial registry update: NOT_YET_RECRUITING. No results reported in the supplied registry record.

RCTRoutine significance
Reporter brief

What this changes

The finding has not established an approved change to our evidence assessment.

Source date: Oct 13, 2026 · Discovered: Oct 13, 2026 · Assessed: — · Research update

What it does not prove

  • No data are provided on study outcomes or findings, making it impossible to assess whether fisetin affected endothelial function or cellular senescence markers.
  • The mechanism linking any effects of fisetin to senescence reduction versus other pathways cannot be determined from this abstract.
  • Safety and tolerability outcomes are not reported.

Extracted from supplied source material; model confidence is not a measured probability of correctness.

Design
Rct
Sample size
—
Duration
—
Population
Older adults
Primary outcome
Vascular endothelial function
Effect size
—
Significance
Not reported
Journal
University of Colorado, Boulder
Published
Oct 13, 2026

Recorded source passages

Abstract or registry material supplied for assessment; source version 1. This is not a claim of full-text review.

This clinical trial will assess if supplementation with the natural compound fisetin can improve vascular endothelial function in older adults
The clinical trial will also assess if any effects of fisetin on endothelial function are associated with reduced cellular senescence
The study will also evaluate safety, tolerability and adherence with fisetin treatment

Assessment history

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