Reporter brief
Targeting Healthy Eating to Maintain Energy While Living With Cancer (THYME) (2668GCCC)
What happened
Trial registry update: NOT_YET_RECRUITING. No results reported in the supplied registry record.
Why it matters
Assessment pending; this report does not establish a change in evidence.
What it does NOT prove
- This is a protocol/trial design paper, not a results report—no efficacy outcomes are presented, so the intervention's actual effect on fatigue or frailty remains unknown.
- The study was powered as a phase II trial to inform a future phase III trial, meaning it was not designed to detect or confirm clinically meaningful effects.
- Causality cannot be inferred from the mechanistic pathway proposed (circadian rhythm entrainment) without direct evidence linking the intervention to both rhythm changes and symptom improvement.
Study design and sample
Rct; Human.
Patients aged 55 years or older with prostate cancer or metastatic breast cancer, with baseline eating window >12 hours, not employed in night-shift work
- Design
- Rct
- Sample
- 132
- Journal
- University of Maryland, Baltimore
- Published
- Sep 17, 2026
Effect size
Not recorded.
Caveats
- Assessment: Unassessed.
- Only the source material recorded on this evidence page was assessed.
Conflicts and funding
Not recorded.
Previous evidence
See the Intermittent fasting timeline and recorded assessment for prior evidence.
Primary source
Cancel Death charts and briefs may be reproduced editorially with attribution to CancelDeath.com. This brief is generated from the primary recorded source facts and assessment. Its review status is shown below; verify quotations against the paper before publication.