Reporter brief
The Effect of Metformin Treatment on Surrogate Markers of Ageing (Leukocyte Telomere Length and Telomerase Activity), Longevity Gene Expression (Sirtuin 1, p66Shc, p53, Andmammalian Target of Rapamycin ), in North Indian Individuals With the Prediabetes: A Randomized Control Trial
What happened
Trial registry update: COMPLETED. No results reported in the supplied registry record.
Why it matters
Assessment pending; this report does not establish a change in evidence.
What it does NOT prove
- This is a study protocol with no reported outcomes—it describes what was planned, not what was found; no conclusions about metformin's effects can be drawn from this document alone.
- Sample size, effect sizes, and statistical significance are not provided, making it impossible to assess the magnitude or reliability of any findings.
- This is a protocol document, not a published results paper, so the trial may not have been completed or the results may not have been made available.
Study design and sample
Rct; Human.
Pre-diabetic individuals from North India
- Design
- Rct
- Sample
- —
- Journal
- Diabetes Foundation, India
- Published
- Dec 24, 2025
Effect size
Not recorded.
Caveats
- Assessment: Unassessed.
- Only the source material recorded on this evidence page was assessed.
Conflicts and funding
Not recorded.
Previous evidence
See the Metformin timeline and recorded assessment for prior evidence.
Primary source
Cancel Death charts and briefs may be reproduced editorially with attribution to CancelDeath.com. This brief is generated from the primary recorded source facts and assessment. Its review status is shown below; verify quotations against the paper before publication.