Creatine
Accessible · Evidence and recent research
Notify me when meaningful evidence changes.
Where things stand
Creatine has useful evidence for high-intensity exercise performance and adaptations to strength training. These outcomes can matter for physical capacity, but performance or lean-mass benefits do not demonstrate longer life. Its role on a longevity site is therefore mainly as a possible aid to maintaining function, with broader ageing claims requiring their own evidence. Source ↗ Recently: The latest trial-registry update in our collection is dated Oct 28, 2026: “Multi-Omic Biomarkers of Response to an Integrated Intervention (Home-Based Multicomponent Exercise Plus Creatine and/or Beta-Hydroxy-Beta-Methylbutyrate [HMB] Supplementation) to Reduce Sarcopenia and Preserve Muscle and Functional Capacity in Huntington's Disease: A Randomized, Double-Blind, Placebo-Controlled, Four-Arm Trial”. Its implications have not yet been summarized in a source-checked review. Read update ↗
AI-written overview · not expert-reviewed · Background sources checked Sep 23, 2026 · Recent updates cover the last 30 days of this collection. A new report does not automatically change the evidence assessment.
Background and coverage
NIH ODS: exercise supplement evidence ↗
- Regulatory status
- Supplement
- Availability
- Widely available
- Category
- Accessible
- Human results verified here
- 0
Evidence collection is not assessed. 0 approved assessments; 3 assessments awaiting review; 0 published studies with verified results. Safety: not assessed.
Recorded evidence activity (experimental)
A numeric breakdown will be available after baseline review. Safety is not yet assessed.
What changed
Evidence events affecting this intervention
Multi-Omic Biomarkers of Response to an Integrated Intervention (Home-Based Multicomponent Exercise Plus Creatine and/or Beta-Hydroxy-Beta-Methylbutyrate [HMB] Supplementation) to Reduce Sarcopenia and Preserve Muscle and Functional Capacity in Huntington's Disease: A Randomized, Double-Blind, Placebo-Controlled, Four-Arm Trial
Trial registry update: NOT_YET_RECRUITING. No results reported in the supplied registry record.
A Prospective, Randomized, Multicenter Clinical Trial on the Effect of a Home-Based Multicomponent Exercise Program Combined With Nutritional Supplementation in Patients With Transthyretin Cardiac Amyloidosis
Trial registry update: COMPLETED. No results reported in the supplied registry record.
Assessment history
The 25 most recent recorded changes, including corrections and backfill
No score history yet
Human studies with verified results
No published human results verified in this collection yet
Animal and mechanistic evidence
No preclinical studies tracked yet