Reporter brief
Chronic Metformin Treatment Induces a Dietary Restriction-like State in Overweight Human
What happened
Trial registry update: UNKNOWN. No results reported in the supplied registry record.
Why it matters
Assessment pending; this report does not establish a change in evidence.
What it does NOT prove
- The study does not establish whether any observed gene expression changes translate to clinical health benefits or reduced disease risk in humans. The abstract does not report the actual findings, results, or effect sizes, making it impossible to assess what was actually discovered. Small sample size (20 per group) and short duration (6 months) limit generalisability to broader populations and long-term effects.
Study design and sample
Rct; Human.
Overweight subjects
- Design
- Rct
- Sample
- 60
- Journal
- Xiang Guang-da
- Published
- Apr 26, 2016
Effect size
Not recorded.
Caveats
- Assessment: Unassessed.
- Only the source material recorded on this evidence page was assessed.
Conflicts and funding
Not recorded.
Previous evidence
See the Metformin timeline and recorded assessment for prior evidence.
Primary source
Cancel Death charts and briefs may be reproduced editorially with attribution to CancelDeath.com. This brief is generated from the primary recorded source facts and assessment. Its review status is shown below; verify quotations against the paper before publication.