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Registry update — unassessed

Dasatinib Plus Quercetin for Accelerated Aging in Mental Disorders

Trial registry update: ACTIVE_NOT_RECRUITING. No results reported in the supplied registry record.

OTHERRoutine significance
Reporter brief

What this changes

The finding has not established an approved change to our evidence assessment.

Source date: Apr 21, 2026 · Discovered: Sep 16, 2026 · Assessed: — · Historical research backfill

What it does not prove

  • Open-label design without control group cannot establish efficacy or isolate drug effects from placebo response. No outcome data were reported, so no claims about the intervention's effects can be evaluated. The study design and population do not determine whether senolytics specifically address aging in psychiatric conditions or only depression/schizophrenia symptoms.

Extracted from supplied source material; model confidence is not a measured probability of correctness.

Design
Other
Sample size
—
Duration
—
Population
—
Primary outcome
—
Effect size
—
Significance
Not reported
Journal
Washington University School of Medicine
Published
Apr 21, 2026

Recorded source passages

Abstract or registry material supplied for assessment; source version 1. This is not a claim of full-text review.

This pilot open-label study examines the effects of a combination of dasatinib plus quercetin - two drugs that have known senolytics properties - on physiological aging in older individuals with depression or schizophrenia.

Source versions

Version 1: Unassessed

Version 1: Superseded

Assessment history

One thread per scientific event, no matter how many outlets covered it.

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