Reporter brief
Involvement of Muscle Mitochondrial Dysfunction in Frailty in Older Adults. Role of Exercise
What happened
Trial registry update: RECRUITING. No results reported in the supplied registry record.
Why it matters
Assessment pending; this report does not establish a change in evidence.
What it does NOT prove
- This is a study protocol describing planned methods, not a report of completed results—no findings about the actual effects of resistance training are presented
- The absence of a control group means the design cannot establish whether observed changes result from the intervention or other factors
- Mechanistic assessments (mitochondrial function, transcriptomics) are proposed but cannot validate whether changes in these cellular markers causally link to clinical improvements in frailty or physical function
Study design and sample
Observational; Human.
approximately 120 participants comprising older adults with type 2 diabetes mellitus, healthy older adults, and young healthy controls
- Design
- Observational
- Sample
- 120
- Journal
- Fundación para la Investigación del Hospital Clínico de Valencia
- Published
- Sep 18, 2026
Effect size
Not recorded.
Caveats
- Assessment: Unassessed.
- Only the source material recorded on this evidence page was assessed.
Conflicts and funding
Not recorded.
Previous evidence
See the Resistance training timeline and recorded assessment for prior evidence.
Primary source
Cancel Death charts and briefs may be reproduced editorially with attribution to CancelDeath.com. This brief is generated from the primary recorded source facts and assessment. Its review status is shown below; verify quotations against the paper before publication.