Lavandula stoechas subsp. luisieri essential oil decreased senescence markers in cultured skin fibroblasts.
In vitro study testing two Lavandula essential oils on etoposide-induced senescent human skin fibroblasts. L. stoechas subsp. luisieri reduced multiple senescence markers (β-galactosidase activity, nuclear alterations, SASP secretion, cell cycle inhibitor expression, and ultrastructural changes) at concentrations as low as 6.25 μg/mL, with greater efficacy than L. pedunculata.
What this changes
The finding has not established an approved change to our evidence assessment.
Source date: Sep 3, 2026 · Discovered: Sep 18, 2026 · Assessed: — · Research update
What it does not prove
- Limitations have not yet been verified. Read the primary source.
Extracted from supplied source material; model confidence is not a measured probability of correctness.
Study details
- Design
- In vitro
- Sample size
- —
- Duration
- —
- Population
- Skin fibroblasts (cell culture); etoposide-induced senescent fibroblasts during recovery phase
- Primary outcome
- Cellular senescence markers (reduction of senescence markers in etoposide-induced fibroblasts)
- Effect size
- L. stoechas subsp. luisieri attained significant effects at 6.25 μg/mL; both oils were effective in decreasing most senescence markers
- Significance
- Mixed
- Journal
- Frontiers in Pharmacology
- Published
- Sep 3, 2026
Sources
Primary source
- Frontiers in pharmacology ↗Peer reviewed
Assessment history
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