Reporter brief
Lavandula stoechas subsp. luisieri essential oil decreased senescence markers in cultured skin fibroblasts.
What happened
In vitro study testing two Lavandula essential oils on etoposide-induced senescent human skin fibroblasts. L. stoechas subsp. luisieri reduced multiple senescence markers (β-galactosidase activity, nuclear alterations, SASP secretion, cell cycle inhibitor expression, and ultrastructural changes) at concentrations as low as 6.25 μg/mL, with greater efficacy than L. pedunculata.
Why it matters
Assessment pending; this report does not establish a change in evidence.
What it does NOT prove
- Limitations have not been recorded; consult the primary source.
Study design and sample
In vitro; In vitro.
Skin fibroblasts (cell culture); etoposide-induced senescent fibroblasts during recovery phase
- Design
- In vitro
- Sample
- —
- Journal
- Frontiers in Pharmacology
- Published
- Sep 3, 2026
Effect size
L. stoechas subsp. luisieri attained significant effects at 6.25 μg/mL; both oils were effective in decreasing most senescence markers
Caveats
- Assessment: Pending.
- Only the source material recorded on this evidence page was assessed.
Conflicts and funding
Not recorded.
Previous evidence
See the Senolytics timeline and recorded assessment for prior evidence.
Primary source
Cancel Death charts and briefs may be reproduced editorially with attribution to CancelDeath.com. This brief is generated from the primary recorded source facts and assessment. Its review status is shown below; verify quotations against the paper before publication.