Registry update — unassessed
Physical Activity Interventions for Sleep Improvement and Sedative-Hypnotic Reduction in Middle-Aged and Older Adults: Investigating the Role of Sarcopenia
Trial registry update: ENROLLING_BY_INVITATION. No results reported in the supplied registry record.
RCTN=180Minor significance
What this changes
The finding has not established an approved change to our evidence assessment.
Source date: Oct 27, 2026 · Discovered: Oct 27, 2026 · Assessed: — · Research update
What it does not prove
- This is a study protocol with no reported results, so it proves nothing about intervention effectiveness. Actual outcomes remain unknown.
- The anticipated results are speculative; whether exercise actually reduces sedative-hypnotic use or improves sleep in this population has not been demonstrated here.
- The role of sarcopenia as a mechanistic link between exercise, sleep, and medication reduction is hypothetical and untested in this proposed study.
Extracted from supplied source material; model confidence is not a measured probability of correctness.
Study details
- Design
- Rct
- Sample size
- 180
- Duration
- 12 months
- Population
- Middle-aged and older adults (aged 50 years and older) with long-term sedative-hypnotic use in Taiwan
- Primary outcome
- Improvement in subjective and objective sleep outcomes and sedative-hypnotic dose reduction in chronic hypnotic users
- Effect size
- —
- Significance
- Not reported
- Journal
- Chang Gung Memorial Hospital
- Published
- Oct 27, 2026
Sources
Primary source
- Chang Gung Memorial Hospital ↗Clinical trial
Recorded source passages
Abstract or registry material supplied for assessment; source version 1. This is not a claim of full-text review.
The aim of this study is to investigate the associations among sarcopenia, sleep disturbances, and sedative-hypnotic use, and to evaluate the effectiveness of a structured physical activity intervention in improving subjective and objective sleep outcomes and promoting dose reduction in chronic hypnotic users.
This three-year study will recruit 180 adults aged 50 years and older who have long-term sedative-hypnotic use. Participants will be randomly assigned to either an individualized 12-week physical activity program or a relaxation training control condition.
Baseline and post-intervention assessments will include subjective sleep questionnaires, polysomnography, muscle strength and mass measurements, and standardized hypnotic dose quantification.
Expected Results: Investigators anticipate that physical activity targeting muscle health will significantly improve sleep quality and contribute to meaningful reductions in sedative-hypnotic medication use among chronic users.
Assessment history
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