Reporter brief
Randomized, Embedded, Multifactorial, Adaptive Platform Trial for Optimizing Surgical Outcomes at UPMC
What happened
Trial registry update: TERMINATED. Results are posted in the registry; assessment pending.
Why it matters
Assessment pending; this report does not establish a change in evidence.
What it does NOT prove
- The abstract provides no outcome data, effect sizes, or results—only the study protocol and objectives, so it cannot demonstrate whether metformin affects surgical outcomes
- The sample size is not reported, making it impossible to assess statistical power or the study's ability to detect meaningful effects
- As a protocol document rather than a completed study report, this provides no evidence about efficacy or safety of metformin in this population
Study design and sample
Rct; Human.
Nondiabetic older adults scheduled for elective surgery
- Design
- Rct
- Sample
- —
- Journal
- Not peer-reviewed; author listed as Matthew Neal MD
- Published
- Jun 18, 2024
Effect size
Not recorded.
Caveats
- Assessment: Unassessed.
- Only the source material recorded on this evidence page was assessed.
Conflicts and funding
Not recorded.
Previous evidence
See the Metformin timeline and recorded assessment for prior evidence.
Primary source
Cancel Death charts and briefs may be reproduced editorially with attribution to CancelDeath.com. This brief is generated from the primary recorded source facts and assessment. Its review status is shown below; verify quotations against the paper before publication.