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Reporter brief

RCT of physical therapy program shows exercise effects on cancer-induced cachexia biomarkers

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This randomized controlled trial compared a 3-month progressive exercise program (aerobic and resistance training) plus standard care versus standard chemotherapy and nutritional counseling alone in patients aged 40-60 receiving neoadjuvant chemotherapy for non-metastatic cancer. The study measured biomarkers related to muscle-bone signaling (myokines and osteokines) and functional physical outcomes to assess whether targeted exercise could attenuate cachexia.

Assessment pending; this report does not establish a change in evidence.

  • Limitations have not been recorded; consult the primary source.

Rct; Human.

Non-metastatic cancer patients aged 40–60 undergoing neoadjuvant chemotherapy

Design
Rct
Sample
—
Journal
Pharos University in Alexandria
Published
Sep 8, 2026

Not recorded.

  • Assessment: Superseded.
  • Only the source material recorded on this evidence page was assessed.

Not recorded.

See the Exercise timeline and recorded assessment for prior evidence.

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