RCT of polyphenol supplementation combined with 12-week exercise in older adults tested feasibility and physical performance.
A randomized controlled pilot feasibility trial examined whether polyphenol supplementation combined with 12 weeks of supervised resistance and aerobic exercise could improve physical function and muscle health in older adults compared to placebo. Participants received either a polyphenol blend or maltodextrin placebo while completing the exercise program. The study included exploratory analysis of muscle biopsies and plasma samples to assess cellular and molecular effects.
What this changes
The finding has not established an approved change to our evidence assessment.
Source date: Aug 27, 2026 · Discovered: Sep 18, 2026 · Assessed: — · Research update
What it does not prove
- Limitations have not yet been verified. Read the primary source.
Extracted from supplied source material; model confidence is not a measured probability of correctness.
Study details
- Design
- Rct
- Sample size
- —
- Duration
- 3 months
- Population
- Older adults experiencing age-related loss of muscle mass, strength, and physical function
- Primary outcome
- Feasibility of implementing a 12-week resistance and aerobic exercise program combined with dietary supplementation in older adults
- Effect size
- —
- Significance
- Not reported
- Journal
- Dr. Chris McGlory, PhD
- Published
- Aug 27, 2026
Sources
Primary source
- Dr. Chris McGlory, PhD ↗Clinical trial
Assessment history
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