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Registry update — unassessed

The Effect of Exercise and Nicotinamide Riboside on Muscle Health and Insulin Resistance in Adult Survivors of Childhood Cancer With Prediabetes: A Pilot Feasibility Study

Trial registry update: ACTIVE_NOT_RECRUITING. No results reported in the supplied registry record.

RCTMinor significance
Reporter brief

What this changes

The finding has not established an approved change to our evidence assessment.

Source date: Oct 23, 2026 · Discovered: Oct 23, 2026 · Assessed: — · Research update

What it does not prove

  • The abstract does not report actual outcomes or effect sizes, so no conclusions can be drawn about whether the intervention worked.
  • As a feasibility pilot study, this was not designed to establish efficacy—only to assess whether such a trial could be conducted.
  • No comparison group data are provided, making it impossible to determine whether observed changes (if any) differed from a control condition.

Extracted from supplied source material; model confidence is not a measured probability of correctness.

Design
Rct
Sample size
—
Duration
—
Population
Adult survivors of childhood cancer with prediabetes (elevated blood sugar level that is not high enough to be considered diabetes)
Primary outcome
Muscle health and insulin resistance
Effect size
—
Significance
Not reported
Journal
City of Hope Medical Center
Published
Oct 23, 2026

Recorded source passages

Abstract or registry material supplied for assessment; source version 1. This is not a claim of full-text review.

This trial studies the effect of exercise and nicotinamide riboside on muscle health and insulin resistance in adult survivors of childhood cancer with prediabetes
Nicotinamide riboside is a dietary supplement which is similar to vitamin B3
Information collected in this study may help the future development of regimens to improve metabolic outcomes such as muscle health and insulin resistance in childhood cancer survivors

Assessment history

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