Registry update — unassessed
The Effect of Semaglutide in Subjects With Non-cirrhotic Non-alcoholic Steatohepatitis
Trial registry update: ACTIVE_NOT_RECRUITING. No results reported in the supplied registry record.
RCTNotable significance
What this changes
The finding has not established an approved change to our evidence assessment.
Source date: Sep 4, 2026 · Discovered: Sep 23, 2026 · Assessed: — · Research update
What it does not prove
- This abstract contains no results, only study design details, so no efficacy claims can be assessed.
- The study is still ongoing (described prospectively), so outcomes remain unknown.
- No information is provided on which specific NASH endpoints (fibrosis, inflammation, liver function, or clinical events) will be measured or have been achieved.
Extracted from supplied source material; model confidence is not a measured probability of correctness.
Study details
- Design
- Rct
- Sample size
- —
- Duration
- 60 months
- Population
- Subjects with non-cirrhotic non-alcoholic steatohepatitis (NASH). Excludes participants with other chronic liver diseases. Excludes pregnant, breast-feeding, or potentially pregnant women.
- Primary outcome
- —
- Effect size
- —
- Significance
- Not reported
- Journal
- Novo Nordisk A/S
- Published
- Sep 4, 2026
Funding: Novo Nordisk A/S (sponsor)
Conflicts: Study is conducted by Novo Nordisk A/S, the manufacturer of semaglutide
Sources
Primary source
- Novo Nordisk A/S ↗Clinical trial
Recorded source passages
Abstract or registry material supplied for assessment; source version 1. This is not a claim of full-text review.
Participants will either get semaglutide or a dummy medicine - which treatment participants get is decided by chance.
The study will last for about 5 years.
Women cannot take part in the study if they are pregnant, breast-feeding or plan to become pregnant during the study period.
Participants with other chronic liver diseases cannot take part in this study.
Assessment history
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