Research feed
Understand the finding first, then explore the evidence. Choose your reading level and sources independently.
Advanced research filters
Dates show original publication, separately from when we added the story. Clinical trials lists registry activity separately. Check collection coverage.
- Observational study· The journal of nutrition, health & aging
Accelerated aging biomarkers linked to higher pancreatic disease risk
In a study of over 326,000 UK adults, measures of accelerated biological aging were associated with increased risk of pancreatic diseases, including cancer and chronic pancreatitis. Blood lipid levels partially explained this association.
Why it matters: These findings may help identify people at higher risk of pancreatic disease through aging measurements, though aging acceleration is not proven to cause these diseases.
AI-assisted explanation · Evidence assessment pending
Read the study · The journal of nutrition, health & aging ↗ - Observational study· Health science reports
Epigenetic aging measures associated with higher mortality in breast cancer cohort study
This cohort study of 399 breast cancer patients from NHANES (1999-2020) examined whether three biological age indicators—calculated from 12 blood-based biomarkers—predicted all-cause mortality over a median 6.67-year follow-up. During this period, 144 deaths occurred. All three measures showed associations with increased mortality: Homeostatic Dysregulation (HR=1.465), Klemera-Doubal Method (HR=1.017), and Phenotypic Age (HR=1.080). Homeostatic Dysregulation performed better for short-term prediction while Phenotypic Age showed better efficacy for longer-term prediction.
Evidence assessment pending
Read the study · Health science reports ↗ - Observational study· Journal of behavioral medicine
Threat-related early adversity associated with impaired danger-safety discrimination in adolescents
This observational study of 168 youth examined whether different types of early life adversity (threat vs. deprivation) were associated with fear responses and accelerated biological aging. Threat-related adversity was associated with impaired discrimination between danger and safety cues during fear conditioning and with greater left amygdala activation to negative stimuli. However, the study found no evidence that fear responses explained the link between threat and accelerated biological aging (advanced puberty or epigenetic age).
Evidence assessment pending
Read the study · Journal of behavioral medicine ↗