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Sleep

Behavioral · Evidence and recent research

Notify me when meaningful evidence changes.

Where things stand

Sleep supports mental and physical health, alertness and day-to-day function. Persistent poor sleep can also signal a treatable condition such as sleep apnea, rather than simply normal ageing. The useful distinction is between improving sleep health and claiming that a particular sleep duration or product will extend lifespan. Source ↗ Recently: The latest trial-registry update in our collection is dated Oct 27, 2026: “Physical Activity Interventions for Sleep Improvement and Sedative-Hypnotic Reduction in Middle-Aged and Older Adults: Investigating the Role of Sarcopenia”. Its implications have not yet been summarized in a source-checked review. Read update ↗

AI-written overview · not expert-reviewed · Background sources checked Sep 23, 2026 · Recent updates cover the last 30 days of this collection. A new report does not automatically change the evidence assessment.

NIA: sleep and older adults ↗

Regulatory status
Not applicable
Availability
Widely available
Category
Behavioral
Human results verified here
0

Evidence collection is needs review. 0 approved assessments; 57 assessments awaiting review; 0 published studies with verified results. Safety: not assessed.

Methodology →

A numeric breakdown will be available after baseline review. Safety is not yet assessed.

Evidence events affecting this intervention

Browse all evidence →
Registry update — unassessed

Physical Activity Interventions for Sleep Improvement and Sedative-Hypnotic Reduction in Middle-Aged and Older Adults: Investigating the Role of Sarcopenia

Trial registry update: ENROLLING_BY_INVITATION. No results reported in the supplied registry record.

RCTN=1801d
Assessment pending

RCT of NightWare wearable device for PTSD-related nightmares and cardiovascular outcomes in veterans

This randomized controlled trial examined whether NightWare, a prescription wrist-wearable device, improves sleep and cardiovascular health in veterans with PTSD-related nightmares. The study aimed to assess the device's effectiveness in these outcomes, though the abstract does not report results, sample size, or effect estimates.

RCT1mo
Assessment pending

RCT evaluates urolithin A and fisetin on sleep quality and aging biomarkers in middle-aged and older adults

This randomized controlled trial compared four groups—placebo, 500 mg urolithin A, 500 mg fisetin, and a 300 mg urolithin A + 200 mg fisetin combination—over 12 weeks in middle-aged and older adults. Participants took daily capsules and underwent assessments at baseline, week 4, and week 12, including sleep quality measures (PSQI, actigraphy, polysomnography), aging biomarkers (DNA methylation, inflammatory cytokines), and gut microbiome analysis. The abstract describes the study design and planned assessments but does not report any results or findings.

RCT1mo

The 25 most recent recorded changes, including corrections and backfill

Historical record correctionSource updated; previous assessment withdrawn
Historical record correctionSource updated; previous assessment withdrawn
Historical record correctionSource updated; previous assessment withdrawn
Historical record correctionSource updated; previous assessment withdrawn

No published human results verified in this collection yet

No preclinical studies tracked yet

Physical Activity Interventions for Sleep Improvement and Sedative-Hypnotic Reduction in Middle-Aged and Older Adults: Investigating the Role of Sarcopenia
NCT07896603N=180ClinicalTrials.gov ↗
Improving Cardiovascular Health in Veterans With PTSD by Treating Trauma-Related Nightmares With NightWare
Evaluation of Urolithin A and Fisetin on Improving Sleep and Aging Biomarkers in Middle-Aged and Older Adults: A Randomized Controlled Trial

Testable statements and where the evidence stands