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Registry update — unassessed

A Phase II Exploratory Clinical Study Investigating the Geroprotective Effect of Metformin in Middle-aged and Elderly People

Trial registry update: RECRUITING. No results reported in the supplied registry record.

RCTRoutine significance
Reporter brief

What this changes

The finding has not established an approved change to our evidence assessment.

Source date: Mar 21, 2025 · Discovered: Sep 15, 2026 · Assessed: — · Historical research backfill

What it does not prove

  • The abstract does not report actual results, outcomes, or effect sizes—it is only a research objective statement, so no efficacy claims can be evaluated
  • Whether metformin produced any measurable effects on aging markers or whether any observed changes were clinically meaningful cannot be determined from the information provided
  • The study design and any findings specific to particular age groups or sex cannot be assessed without results data

Extracted from supplied source material; model confidence is not a measured probability of correctness.

Design
Rct
Sample size
—
Duration
—
Population
Middle-aged and elderly males
Primary outcome
Geroprotective effect of metformin; aging process mitigation
Effect size
—
Significance
Not reported
Journal
Xuanwu Hospital, Beijing
Published
Mar 21, 2025

Recorded source passages

Abstract or registry material supplied for assessment; source version 1. This is not a claim of full-text review.

A Phase II Exploratory Clinical Study Investigating the Geroprotective Effect of Metformin in Middle-aged and Elderly People
The objective of this research is to assess the efficacy of oral metformin in mitigating the aging process in middle-aged and elderly males, to pinpoint sensitive indicators of human senescence, and to offer innovative frameworks and scientific insights for pharmaceutical interventions in aging.

Source versions

Version 1: Superseded

Version 1: Unassessed

Assessment history

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