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Registry update — unassessed

Effect of Egg Albumin and Agave Fructan Supplementation Combined With Functional Exercise on Muscle Mass, Physical Function, and Inflammatory Status in Patients Receiving Hemodialysis: A Randomized Controlled Trial

Trial registry update: ACTIVE_NOT_RECRUITING. No results reported in the supplied registry record.

RCTN=66Minor significance
Reporter brief

What this changes

The finding has not established an approved change to our evidence assessment.

Source date: Oct 16, 2026 · Discovered: Oct 16, 2026 · Assessed: — · Research update

What it does not prove

  • The specific contributions of exercise versus nutritional supplementation cannot be separated—the benefit may derive primarily from one component rather than their combination. Effect sizes are not reported, so the magnitude of clinical significance is unknown. The study was conducted at a single hospital in Mexico, limiting generalizability to other hemodialysis populations or settings.

Extracted from supplied source material; model confidence is not a measured probability of correctness.

Design
Rct
Sample size
66
Duration
6 months
Population
Adult participants receiving maintenance hemodialysis at Centenario Hospital Miguel Hidalgo
Primary outcome
Muscle mass and physical function
Effect size
—
Significance
Not reported
Journal
Centenario Hospital Miguel Hidalgo
Published
Oct 16, 2026

Recorded source passages

Abstract or registry material supplied for assessment; source version 1. This is not a claim of full-text review.

Patients receiving maintenance hemodialysis frequently develop loss of muscle mass, reduced physical function, and chronic inflammation
This randomized controlled trial will evaluate whether oral supplementation with egg albumin and agave fructans combined with a structured functional exercise program improves muscle mass, physical function, muscle strength, inflammatory status, phase angle, and quality of life compared with nutritional supplementation alone
A total of 66 adult participants receiving maintenance hemodialysis at Centenario Hospital Miguel Hidalgo will be randomly assigned to one of the two intervention groups and followed for 6 months

Assessment history

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