Registry update — unassessed
Effect of β-Hydroxy-β-Methylbutyrate Supplementation Combined With the Vivifrail Multicomponent Exercise Program on Body Composition, Handgrip Strength and Functional Physical Performance in Women Over 60 Years of Age in Tulancingo de Bravo, Hidalgo: A Randomized, Double-Blind, Placebo-Controlled Trial
Trial registry update: NOT_YET_RECRUITING. No results reported in the supplied registry record.
RCTMinor significance
What this changes
The finding has not established an approved change to our evidence assessment.
Source date: Oct 29, 2026 · Discovered: Oct 29, 2026 · Assessed: — · Research update
What it does not prove
- The abstract does not report actual results, so it is unclear whether HMB combined with exercise showed any benefit over exercise plus placebo
- The study design combines two interventions (HMB and structured exercise), making it impossible to isolate the effect of HMB supplementation alone
- No information is provided about effect sizes, statistical significance, or outcome data
Extracted from supplied source material; model confidence is not a measured probability of correctness.
Study details
- Design
- Rct
- Sample size
- —
- Duration
- 3 months
- Population
- Women over 60 years of age in Tulancingo de Bravo, Hidalgo, Mexico
- Primary outcome
- Handgrip strength
- Effect size
- —
- Significance
- Not reported
- Journal
- Universidad Autónoma del Estado de Hidalgo
- Published
- Oct 29, 2026
Sources
Primary source
- Universidad Autónoma del Estado de Hidalgo ↗Clinical trial
Recorded source passages
Abstract or registry material supplied for assessment; source version 1. This is not a claim of full-text review.
The goal of this clinical trial is to learn whether taking a daily supplement of β-hydroxy-β-methylbutyrate (HMB) while following a structured exercise program improves body composition, muscle strength and physical performance in older women.
The main question it aims to answer is: does HMB (3 g per day) combined with the Vivifrail multicomponent exercise program improve handgrip strength more than the same exercise program combined with maltodextrin without HMB?
Participants will take the assigned supplement every day for 12 weeks, attend three supervised Vivifrail exercise sessions per week at the Casa Club de la Tercera Edad (DIF Tulancingo, Hidalgo, Mexico), and complete evaluations at baseline, week 6 and week 12.
Assessment history
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