Injectable klotho-follistatin plasmid gene therapy assessed for safety in healthy adults in uncontrolled pilot study
This pilot study investigated the safety and efficacy of a combination klotho and follistatin gene therapy delivered via nonviral plasmid injection in healthy adult volunteers. The study sought to evaluate both safety outcomes and potential cognitive and health benefits, though no specific results are reported in the abstract.
What this changes
The finding has not established an approved change to our evidence assessment.
Source date: Aug 27, 2026 · Discovered: Sep 15, 2026 · Assessed: — · Research update
What it does not prove
- Limitations have not yet been verified. Read the primary source.
Extracted from supplied source material; model confidence is not a measured probability of correctness.
Study details
- Design
- Observational
- Sample size
- —
- Duration
- —
- Population
- healthy adult volunteers
- Primary outcome
- safety and efficacy of combination klotho and follistatin gene therapy
- Effect size
- —
- Significance
- Not reported
- Journal
- Minicircle
- Published
- Aug 27, 2026
Sources
Primary source
- Minicircle ↗Clinical trial
Source versions
Assessment history
9/24/2026 · SUPERSEDED: Source updated; assessment withdrawn pending review.
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