Pilot RCT of fisetin for vascular function in older adults reports no results.
This is a pilot randomised controlled trial designed to test whether intermittent fisetin treatment improves vascular endothelial function and reduces aortic stiffness in older adults. The trial aimed to explore potential mechanisms including mitochondrial oxidative stress, cellular senescence, and SASP factors. No results or findings are reported.
What this changes
The finding has not established an approved change to our evidence assessment.
Source date: Nov 12, 2025 · Discovered: Sep 16, 2026 · Assessed: — · Research update
What it does not prove
- Limitations have not yet been verified. Read the primary source.
Extracted from supplied source material; model confidence is not a measured probability of correctness.
Study details
- Design
- Rct
- Sample size
- —
- Duration
- —
- Population
- Older adults
- Primary outcome
- Vascular endothelial function and aortic stiffness
- Effect size
- —
- Significance
- Not reported
- Journal
- University of Colorado, Boulder
- Published
- Sep 25, 2026
Sources
Primary source
- University of Colorado, Boulder ↗Clinical trial
Source versions
Assessment history
9/23/2026 · SUPERSEDED: Source updated; assessment withdrawn pending review.
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