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Assessment superseded

Randomized trial of rapamycin versus placebo for aging effects in older adults; safety and efficacy assessed

PEARL was a prospective, double-blind, placebo-controlled randomized trial examining rapamycin's safety and efficacy in reducing clinical measures of aging in older adults. The abstract does not report the sample size, which study arms were compared, what outcome measures were used, or what effects were observed.

RCTRoutine significance
Reporter brief

What this changes

The finding has not established an approved change to our evidence assessment.

Source date: Jan 24, 2024 · Discovered: Sep 19, 2026 · Assessed: — · Research update

What it does not prove

  • Limitations have not yet been verified. Read the primary source.

Extracted from supplied source material; model confidence is not a measured probability of correctness.

Design
Rct
Sample size
—
Duration
—
Population
Healthy older adult population
Primary outcome
Safety and efficacy in reducing clinical measures of aging
Effect size
—
Significance
Not reported
Journal
AgelessRx
Published
Jan 24, 2024

Source versions

Version 1: Unassessed

Version 1: Superseded

Assessment history

9/24/2026 · SUPERSEDED: Source updated; assessment withdrawn pending review.

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