Rapamycin
mTOR inhibitor with the strongest animal lifespan evidence.
Notify me when meaningful evidence changes.
0
Insufficient evidence · Stable
No history yet
⚠ Prescription or off-label use
An immunosuppressant approved for transplant and specific conditions. Use for longevity is off-label, and the dosing used in ageing research differs substantially from approved regimens.
Current assessment
The most reproducible lifespan extension in mammalian models. Human evidence is limited to small trials of immune function and related markers.
- Regulatory status
- Approved other indication
- Availability
- Prescription only
- Category
- Experimental off label
- Human studies tracked
- 0
Evidence breakdown
Human evidence
0
Animal evidence
0
Mechanistic
0
Safety
50
What changed
Evidence events affecting this intervention
No published evidence events yet
Evidence timeline
Every recorded score change
No score history yet
Major human studies
No human studies tracked yet
Animal and mechanistic evidence
No preclinical studies tracked yet