RCT of rapamycin on muscle in older men: effects alone and with resistance exercise.
This is a planned RCT that aimed to recruit 16 healthy men over 50 years old to investigate how rapamycin (a mTOR inhibitor) affects muscle mass and function, both as monotherapy and combined with resistance exercise training. The source provided only the study rationale and design intent, with no outcome data reported.
What this changes
The finding has not established an approved change to our evidence assessment.
Source date: Apr 10, 2025 · Discovered: Sep 19, 2026 · Assessed: — · Research update
What it does not prove
- Limitations have not yet been verified. Read the primary source.
Extracted from supplied source material; model confidence is not a measured probability of correctness.
Study details
- Design
- Rct
- Sample size
- 16
- Duration
- —
- Population
- Healthy male volunteers over 50 years old
- Primary outcome
- Effects of Rapamune on aged human muscle mass and function
- Effect size
- —
- Significance
- Not reported
- Journal
- University of Nottingham
- Published
- Apr 10, 2025
Sources
Primary source
- University of Nottingham ↗Clinical trial
Source versions
Assessment history
9/24/2026 · SUPERSEDED: Source updated; assessment withdrawn pending review.
Discussion (0)
One thread per scientific event, no matter how many outlets covered it.
No comments yet
Be the first to weigh in on this evidence.