Topical rapamycin tested in RCT to assess effects on skin epigenetic aging markers
This was a randomized controlled trial investigating whether topical rapamycin ointment applied to forearms could induce epigenetic changes in skin tissue. The study specifically tested whether the drug could reverse inflammation and reset epigenetic aging markers locally in the skin.
What this changes
The finding has not established an approved change to our evidence assessment.
Source date: Jul 19, 2023 · Discovered: Sep 19, 2026 · Assessed: — · Research update
What it does not prove
- Limitations have not yet been verified. Read the primary source.
Extracted from supplied source material; model confidence is not a measured probability of correctness.
Study details
- Design
- Rct
- Sample size
- —
- Duration
- —
- Population
- —
- Primary outcome
- Epigenetic changes in the skin
- Effect size
- —
- Significance
- Not reported
- Journal
- The University of Texas Health Science Center at San Antonio
- Published
- Jul 19, 2023
Sources
Primary source
Source versions
Assessment history
9/24/2026 · SUPERSEDED: Source updated; assessment withdrawn pending review.
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