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Assessment superseded

RCT of metformin for sarcopenia prevention in older adults with prediabetes showed no reported effect size

This RCT examined whether metformin could prevent sarcopenia in older adults with prediabetes. The study was motivated by evidence that insulin resistance increases sarcopenia risk in older people. No effect size or outcomes data were reported in the abstract.

RCTNotable significance
Reporter brief

What this changes

The finding has not established an approved change to our evidence assessment.

Source date: Feb 11, 2020 · Discovered: Sep 15, 2026 · Assessed: — · Research update

What it does not prove

  • Limitations have not yet been verified. Read the primary source.

Extracted from supplied source material; model confidence is not a measured probability of correctness.

Design
Rct
Sample size
—
Duration
—
Population
—
Primary outcome
—
Effect size
—
Significance
Not reported
Journal
VA Office of Research and Development
Published
Feb 11, 2020

Source versions

Version 1: Superseded

Version 1: Unassessed

Assessment history

9/23/2026 · SUPERSEDED: Source updated; assessment withdrawn pending review.

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