Systematic review examines molecular mechanisms of skin aging and therapeutic approaches including stem cell therapy.
This is a narrative review that describes the phenotypes and mechanisms of skin aging, including reduced regenerative capacity, chronic inflammation, impaired barrier function, oxidative stress, DNA damage, and epigenetic alterations. The authors evaluate recent research on pharmacological interventions and stem cell therapy for mitigating skin aging, along with delivery systems for natural compounds and the potential of AI in drug discovery. No specific efficacy data or effect sizes for stem cell therapy are reported.
What this changes
The finding has not established an approved change to our evidence assessment.
Source date: Sep 1, 2026 · Discovered: Sep 21, 2026 · Assessed: — · Research update
What it does not prove
- Limitations have not yet been verified. Read the primary source.
Extracted from supplied source material; model confidence is not a measured probability of correctness.
Study details
- Design
- Systematic review
- Sample size
- —
- Duration
- —
- Population
- Skin, the body's largest organ
- Primary outcome
- Mechanisms and phenotypes of skin aging
- Effect size
- —
- Significance
- Not reported
- Journal
- Journal of cellular and molecular medicine
- Published
- Sep 1, 2026
Sources
Primary source
- Journal of cellular and molecular medicine ↗Peer reviewed
Assessment history
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