Registry update — unassessed
Training the Aging Brain Through Speed: Examining Cerebrovascular Adaptations Associated With Motor-Cognitive Performance Following High-Velocity Resistance Training in Older Adults at Risk for AD/ADRD
Trial registry update: NOT_YET_RECRUITING. No results reported in the supplied registry record.
RCTMinor significance
What this changes
The finding has not established an approved change to our evidence assessment.
Source date: Oct 14, 2026 · Discovered: Oct 14, 2026 · Assessed: — · Research update
What it does not prove
- No efficacy results are reported; this is a protocol description, not a completed study with findings. Whether high-velocity resistance training actually improves cognition, cerebrovascular regulation, or any other outcome cannot be determined from this document. Whether observed changes in blood flow causally relate to cognitive improvements cannot be established from an RCT alone without mechanistic validation.
Extracted from supplied source material; model confidence is not a measured probability of correctness.
Study details
- Design
- Rct
- Sample size
- —
- Duration
- 3 months
- Population
- Adults ages 60 to 79 at higher risk for Alzheimer's disease and related dementias
- Primary outcome
- Improvements in thinking skills such as executive function and processing speed; improvements in cerebrovascular regulation of blood flow during cognitive testing, changes in blood pressure, and controlled breathing tasks
- Effect size
- —
- Significance
- Not reported
- Journal
- University of Illinois at Chicago
- Published
- Oct 14, 2026
Sources
Primary source
- University of Illinois at Chicago ↗Clinical trial
Recorded source passages
Abstract or registry material supplied for assessment; source version 1. This is not a claim of full-text review.
The goal of this clinical trial is to learn whether a 12-week high-velocity resistance training program can improve brain blood flow and thinking skills in adults ages 60 to 79 who are at higher risk for Alzheimer's disease and related dementias.
Participants will complete two study visits at the University of Illinois Chicago, one before the program begins and one after 12 weeks.
After the first visit, participants will be randomly assigned, like flipping a coin, to one of two groups. One group will take part in supervised resistance training three times per week for 12 weeks at the University of Illinois Chicago. Each session will last about 60 minutes and will be supervised by trained exercise professionals. The other group will continue their usual daily activities for 12 weeks and then return for follow-up testing.
Assessment history
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